EFEITOS DOS AGONISTAS DO RECEPTOR DE GLP-1 SOBRE O COMPORTAMENTO ALIMENTAR EM INDIVÍDUOS COM OBESIDADE: REVISÃO INTEGRATIVA DA LITERATURA

Abstract

Obesity is a chronic multifactorial condition associated with metabolic, physiological, and behavioral changes, with eating behavior being one of the main factors related to its development and maintenance. In this context, glucagon-like peptide-1 (GLP-1) receptor agonists have emerged as an effective therapeutic alternative for obesity treatment, mainly due to their role in appetite and satiety regulation. This study aimed to analyze the effects of GLP-1 receptor agonists on eating behavior in individuals with obesity through an integrative literature review. The research was conducted using scientific databases, considering articles published between 2018 and 2025 in Portuguese and English, addressing the effects of semaglutide and tirzepatide on food intake, satiety, food preferences, and subjective aspects of eating behavior. Five studies that met the inclusion criteria were selected. The results showed that these medications promote appetite reduction, increased satiety, decreased caloric intake, and positive changes in eating patterns and hedonic responses to food. However, longterm effects still require further investigation, especially regarding the maintenance of behavioral changes after treatment discontinuation. It is concluded that GLP-1 receptor agonists have favorable effects on food control and obesity treatment, particularly when combined with nutritional and behavioral follow-up.