ATUALIZAÇÕES NA TERAPÊUTICA DA DERMATITE ATÓPICA EM CÃES - REVISÃO DE LITERATURA

Abstract

Canine atopic dermatitis (CAD) is a chronic, pruritic inflammatory condition related to genetic and environmental factors and dysfunction of the physiological barrier, which favors immunity to allergens and pathogens. The pathophysiology of the disease involves loss of ceramides and alterations in filaggrin, proteins essential for skin integrity. Treatment has advanced with the use of immunosuppressive, anti-inflammatory and biological therapies, with medications with controlled side effects, in addition to strategies to restore the barrier and reduce exposure to allergens. The therapeutic approach is divided into two phases: immediate control of symptoms, with fast-acting medications, and maintenance to prevent flare-ups, reducing the severity and frequency of crises. A multimodal strategy, which includes topical, systemic and environmental treatments, is essential for effective management, and a personalized plan for each patient is essential. Diagnosis is made through clinical history and physical examinations, which help identify the cause. Although polytherapy is recommended, it is important to choose medications based on efficacy and side effects. Continuous monitoring is crucial to avoid consequences arising from prolonged use of treatments.through clinical history and physical examinations, which help identify the cause. Although polytherapy is recommended, it is important to choose medications based on efficacy and side effects. Continuous monitoring is crucial to avoid consequences arising from prolonged use of treatments.